- What are the evidence-based guidelines for discontinuation or modification of anticoagulation therapy for patients requiring emergency orthopedic surgical intervention?
- What are the evidence-based guidelines for the use of dalteparin pre- and post-hip surgery for patients requiring emergency orthopedic surgical intervention?
One evidence-based guideline was identified that provides recommendations for pre- and post-surgical doses and frequency of dalteparin administration for VTE prophylaxis in surgical patients; 5000 units of dalteparin subcutaneously were recommended at 12 hours before surgery, followed by 5000 units delivered once daily post-operatively. Potential modifications for high-risk situations were also offered. No evidence-based guidelines were identified regarding treatment of patients on existing anticoagulation therapy requiring emergency orthopedic surgical intervention.